| Entry | Bombinin-like peptides 3 |
| Uniprot code | P29004 |
| Fasta | P29004 |
| Peptide names | Bombinin-like peptide 3 Bombinin-like peptides 3 BLP-3 GH-1 peptide |
| Suborder | Archeobatrachia |
| Family | Bombinatoridae |
| Genus | Bombina |
| Species | Bombina orientalis |
| Ecozone | Palearctic |
| Distribution | Southern part of Russian Far East (Primorye Region and a few localities in the Khabarovskii Region); northeastern China (from northeastern Inner Mongolia and Heilongjiang south to southern Liaoning, with one locality in the Beijing area and other records in eastern Shandong and eastern Jiangsu) and Korea; Tsushima and Kyushu Islands, Japan |
| Antimicrobial & other activities | antibacterial, antifungal |
| Tissue | Skin, Brain, Stomach |
| Sequence | MNFKYIVAVSILIASAYARSEENDIQSLSQRDVLEEESLREIRGIGAAILSAGKSALKGL AKGLAEHFGKRTAEDHEVMKRLEAAIHSLSQRDVLEEESLREIRGIGAAILSAGKSALKG LAKGLAEHFGKRTAEEHEMMKRLEAVMRDLDSLDYPEEASEMETRSFNQEEIANLYTKKE KRILGPILGLVSNALGGLLG |
| Length | 200 |
| Signal peptide class | Class-3 |
| References: | |
| 1. for MIC/HC50 | M. Simmaco et al. / Biochimica et Biophysica Acta 1788 (2009) 1551-1555. Bombinins, antimicrobial peptides from Bombina species |
| 2. for other activities | B.W. Gibson et al. / The Journal of Biological Chemistry 266 (1991) 23103-23111. Bombinin-like peptides with antimicrobial activity from scin secreations from Asian toad, Bombina orientalis |
| Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
| Signal | 18 | MNFKYIVAVSILIASAYA | |||||
| Prepro | 25 | RSEENDIQSLSQRDVLEEESLREIR | |||||
| Bioactive | Bombinin-like peptide 3 | 25 | Yes | GIGAAILSAGKSALKGLAKGLAEHF | 0.9 | 1.7 | |
| Prepro | 36 | GKRTAEDHEVMKRLEAAIHSLSQRDVLEEESLREIR | |||||
| Bioactive | Bombinin-like peptide 3 | 25 | Yes | GIGAAILSAGKSALKGLAKGLAEHF | 0.9 | 1.7 | |
| Prepro | 53 | GKRTAEEHEMMKRLEAVMRDLDSLDYPEEASEMETRSFNQEEIANLYTKKEKR | |||||
| Bioactive | GH-1 peptide | 18 | No | ILGPILGLVSNALGGLLG |