Gaegurin-5

Entry Gaegurin-5
Uniprot code P80399
Fasta P80399
Peptide names Gaegurin-5 GGN5 Brevinin-1EMa
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Glandirana rugosa
Ecozone Palearctic
Distribution Honshu, Shikoku, and Kyushu Islands, Japan; introduced into Hawaii, USA
Antimicrobial & other activities antibacterial, anticancer
Tissue Skin
Sequence MFTLKKSLLLLFFLGTISLSLCEEERNADEEEKRDVEVEKRFLGALFKVASKVLPSVFCA
ITKKC
Length 65
Signal peptide class Class-1
References:
2. for other activities H-S. Won et al. / Biochimica et Biophysica Acta 1788 (2009) 1620-1629. Action mechanism and structural requirements of the antimicrobial peptides, gaegurins


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTISLSLC    
Prepro19 EEERNADEEEKRDVEVEKR   
BioactiveGaegurin-524NoFLGALFKVASKVLPSVFCAITKKC