Entry
Dermaseptin DRG3
Uniprot code
P81488
Fasta
P81488
Peptide names
Dermaseptin DRG3
Suborder
Neobatrachia
Family
Hylidae
Genus
Phyllomedusa
Species
Phyllomedusa bicolor
Ecozone
Neotropic
Distribution
Amazon Basin in Brazil, Colombia, Bolivia, and Peru; the Guianan region of Venezuela and the Guianas. Possibly to be found in eastern Ecuador
Antimicrobial & other activities
antibacterial
Tissue
Skin
Sequence
MAFLKKSLFLVLFLGLVSLSVCEEEKRENEDEEEQEDDEQSEEKRALWKTIIKGAGKMIG
Length
77
Signal peptide class
Class-1
References:
1. for MIC/HC50
Y. Fleury et al. / Biochimica et Biophysica Acta 1396 (1998) 228-236. Synthesis, antimicrobial activity and gene structure of a novel member of the dermaseptin B family
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
22
MAFLKKSLFLVLFLGLVSLSVC
Prepro 23 EEEKRENEDEEEQEDDEQSEEKR Bioactive Dermaseptin DRG3 30 No ALWKTIIKGAGKMIGSLAKNLLGSQAQPES 50 50