Preprophylloxin

Entry Preprophylloxin
Uniprot code P81565
Fasta P81565
Peptide names Phylloxin Preprophylloxin
Suborder Neobatrachia
Family Hylidae
Genus Phyllomedusa
Species Phyllomedusa bicolor
Ecozone Neotropic
Distribution Amazon Basin in Brazil, Colombia, Bolivia, and Peru; the Guianan region of Venezuela and the Guianas. Possibly to be found in eastern Ecuador
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MVFLKKSLLLVLFVGLVSLSICEENKREEHEEIEENKEKAEEKRGWMSKIASGIGTFLSG
MQQG
Length 64
Signal peptide class Class-1
References:
2. for other activities T.N. Pierre et al. / European Journal of Biochemistry 267 (2000) 370-378. Phylloxin, a novel peptide antibiotic of the dermaseptin family of antimicrobial/opioid peptide precursors


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MVFLKKSLLLVLFVGLVSLSIC    
Prepro22 EENKREEHEEIEENKEKAEEKR   
BioactivePhylloxin19NoGWMSKIASGIGTFLSGMQQ