Entry
Kininogen-2
Uniprot code
P83057
Fasta
P83057
Peptide names
[Val1,Thr3,Thr6]-bradykinin Kininogen-2 Kininogen-2-associated peptide
Suborder
Archeobatrachia
Family
Bombinatoridae
Genus
Bombina
Species
Bombina variegata
Ecozone
Palearctic
Distribution
Europe excluding the Iberian Peninsula and Italy south of the Po River in Italy, east to western Ukraine and Moldova; introduced into England
Antimicrobial & other activities
contraction of small intestine smooth muscle cells, relaxation of arterial smooth muscle cells
Tissue
Skin
Sequence
MILWFCLNFLIVLCLEHFPGTLAAERNVPQSEEKTEQFLRDLSEISRLQRVPTGFTPFRG
Length
96
Signal peptide class
Class-5
References:
2. for other activities
T. Chen et al. / European Journal of Biochemistry 269 (2002) 4693-4700. Novel bradykinins and their precursor cDNAs from European yellow-bellied toad (Bombina variegata) skin
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
23
MILWFCLNFLIVLCLEHFPGTLA
Prepro 27 AERNVPQSEEKTEQFLRDLSEISRLQR Bioactive [Val1,Thr3,Thr6]-bradykinin 9 No VPTGFTPFR Prepro 16 GKFHSQSLRGLSETKK Bioactive Kininogen-2-associated peptide 17 No FKAPYNIHWHCKPGLLC