| Entry | Kininogen-1 |
| Uniprot code | P83060 |
| Fasta | P83060 |
| Peptide names | Bradykinin Kininogen-1 |
| Suborder | Archeobatrachia |
| Family | Bombinatoridae |
| Genus | Bombina |
| Species | Bombina orientalis |
| Ecozone | Palearctic |
| Distribution | Southern part of Russian Far East (Primorye Region and a few localities in the Khabarovskii Region); northeastern China (from northeastern Inner Mongolia and Heilongjiang south to southern Liaoning, with one locality in the Beijing area and other records in eastern Shandong and eastern Jiangsu) and Korea; Tsushima and Kyushu Islands, Japan |
| Antimicrobial & other activities | contraction of small intestine smooth muscle cells, relaxation of arterial smooth muscle cells |
| Tissue | Skin |
| Sequence | MRLWFCLSFFIILCLEHFPGTLADERNVPESEEKTEQFLRDLSEISRLQRRPPGFSPFRG KFHSQSLRDLSEISRLQRRPPGFSPFRGKFHSQSMRDLSEISRLQRRPPGFSPFRGKFHS QSMRDLSEISRLQRRPPGFSPFRGKFHSQSLRGLSEIKRLKTTHKIH |
| Length | 167 |
| Signal peptide class | Class-5 |
| References: | |
| 2. for other activities | T. Chen et al. / Peptides 23 (2002) 1547-1555. Bradykinins and their precursor cDNAs from the skin of the fire-bellied toad (Bombina orientalis) |
| Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
| Signal | 23 | MRLWFCLSFFIILCLEHFPGTLA | |||||
| Prepro | 27 | DERNVPESEEKTEQFLRDLSEISRLQR | |||||
| Bioactive | Bradykinin | 9 | No | RPPGFSPFR | |||
| Prepro | 19 | GKFHSQSLRDLSEISRLQR | |||||
| Bioactive | Bradykinin | 9 | No | RPPGFSPFR | |||
| Prepro | 19 | GKFHSQSMRDLSEISRLQR | |||||
| Bioactive | Bradykinin | 9 | No | RPPGFSPFR | |||
| Prepro | 19 | GKFHSQSMRDLSEISRLQR | |||||
| Bioactive | Bradykinin | 9 | No | RPPGFSPFR |