Maximin 1/H1

Entry Maximin 1/H1
Uniprot code P83080
Fasta P83080
Peptide names Maximin 1/H1 Maximin 1 Maximin H1
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal, anticancer; Maximin H1: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLLASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKILGGVKTALKGA
LKELASTYANGKRTAEEHEVMKRLEAVMRDLDSLDYPEEAAERETRSFNQEEIANLFTKK
EKRILGPVISTIGGVLGGLLKNLG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLLASAYA    
Prepro25 RSEENDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 127YesGIGTKILGGVKTALKGALKELASTYAN 7.297.29
Prepro53 GKRTAEEHEVMKRLEAVMRDLDSLDYPEEAAERETRSFNQEEIANLFTKKEKR   
BioactiveMaximin H120YesILGPVISTIGGVLGGLLKNL 4.662.33