Entry | Maximin 1/H1 |
Uniprot code | P83080 |
Fasta | P83080 |
Peptide names | Maximin 1/H1 Maximin 1 Maximin H1 |
Suborder | Archeobatrachia |
Family | Bombinatoridae |
Genus | Bombina |
Species | Bombina maxima |
Ecozone | Palearctic, Indomalaya |
Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
Antimicrobial & other activities | antibacterial, antifungal, anticancer; Maximin H1: antibacterial, antifungal |
Tissue | Skin |
Sequence | MNFKYIVAVSFLLASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKILGGVKTALKGA LKELASTYANGKRTAEEHEVMKRLEAVMRDLDSLDYPEEAAERETRSFNQEEIANLFTKK EKRILGPVISTIGGVLGGLLKNLG |
Length | 144 |
Signal peptide class | Class-3 |
References: | |
1. for MIC/HC50 | R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 18 | MNFKYIVAVSFLLASAYA | |||||
Prepro | 25 | RSEENDEQSLSQRDVLEEESLREIR | |||||
Bioactive | Maximin 1 | 27 | Yes | GIGTKILGGVKTALKGALKELASTYAN | 7.29 | 7.29 | |
Prepro | 53 | GKRTAEEHEVMKRLEAVMRDLDSLDYPEEAAERETRSFNQEEIANLFTKKEKR | |||||
Bioactive | Maximin H1 | 20 | Yes | ILGPVISTIGGVLGGLLKNL | 4.66 | 2.33 |