Phylloseptin-7

Entry Phylloseptin-7
Uniprot code P84572
Fasta P84572
Peptide names Phylloseptin-P1 Phylloseptin-7 Phylloseptin 7 PS-7
Suborder Neobatrachia
Family Hylidae
Genus Phyllomedusa
Species Phyllomedusa hypochondrialis
Ecozone Neotropic
Distribution Eastern Colombia east through northern and eastern Venezuela, through the Guianas and throughout Brazilian Amazonia; currently not known from Amazonian Colombia, Peru, Ecuador, or Bolivia
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MAFLKKSLFLVLFLGLVSLSICEEEKRETEEEENEQEDDDKSEEKRFLSLIPHAINAVSA
IAKHFG
Length 66
Signal peptide class Class-1
References:
1. for MIC/HC50 A.H. Thompson et al. / Peptides 28 (2007) 1331-1343. A combined mass spectrometric and cDNA sequencing approach to the isolation and characterization of novel antimicrobial peptides from the skin secretions of Phyllomedusa hypochondrialis azurea


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MAFLKKSLFLVLFLGLVSLSIC    
Prepro24 EEEKRETEEEENEQEDDDKSEEKR   
BioactivePhylloseptin-719YesFLSLIPHAINAVSAIAKHF 7.23.6