Brevinin-1E

Entry Brevinin-1E
Uniprot code P84839
Fasta P84839
Peptide names Brevinin-1E
Suborder Neobatrachia
Family Ranidae
Genus Pelophylax
Species Pelophylax saharicus
Ecozone Palearctic
Distribution Morocco (and adjacent Western Sahara) to Tunisia and northern Libya, Siwa Oasis, northwestern Egypt. Also known from localities near the Hoggar Massic in southern Algeria; Ceuta and Melilla (Spain)
Antimicrobial & other activities antibacterial, antifungal, insulin releasing
Tissue Skin
Sequence
Length 24
References:
1. for MIC/HC50 Mi-Yun Kwon et al. / Biochimica et Biophysica Acta 1387 (1998) 239-248. Structure-activity analysis of brevinin 1E amide, an antimicrobial peptide from Rana esculenta
2. for other activities L. Marenah et al. / Journal of Endocrinology 188 (2006) 1-9. Skin secretions of Rana saharica frogs reveal antimicrobial peptides esculentins-1 and -1B and brevinins-1E and -2EC with novel insulin releasing activity


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveBrevinin-1E24YesFLPLLAGLAANFLPKIFCKITRKC0.412.332.33