Caerin 1.1

Entry Caerin 1.1
Uniprot code P86484
Fasta P86484
Peptide names Caerin-1.1 Caerin 1.1
Suborder Neobatrachia
Family Hylidae
Genus Litoria
Species Litoria peronii
Ecozone Australasia
Distribution Southeastern Queensland, eastern New South Wales, Victoria to the River Murray and extreme southeastern South Australia along the River Murray and in the extreme lower south-east, Australia
Antimicrobial & other activities antibacterial, anticancer, antifungal, nNOS inhibitor
Tissue Skin
Sequence
Length 25
References:
1. for MIC/HC50 M.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance;  P.A. Wabnitz et al. / European Journal of Biochemistry 267 (2000) 269-275. Differences in the skin peptides of the male and female Australian tree frog Litoria splendida. The discovery of the aquatic male sex pheromone splendipherin, together with phe8 caerulein and a new antibiotic peptide caerin 1.10
2. for other activities R.J. Jackway et al. / Peptides 32 (2011) 161-172. Skin peptide and cDNA profiling of Australian anurans: genus and species identification and evolutionary trends


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveCaerin 1.125YesGLLSVLGSVAKHVLPHVVPVIAEHL  1.16