Esculentin-2S

Entry Esculentin-2S
Uniprot code Q1MU20
Fasta Q1MU20
Peptide names Esculentin-2S
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana schmackeri
Ecozone Palearctic, Indomalaya
Distribution Southern and south-central China in Henan, Shaanxi, Gansu, Sichuan, Guizhou, Hubei, Anhui, Jiangsu, Zhejiang, Hunan, Guangdong and Guangxi Provinces, at 200-1400 m elevation; reports from Vietnam and Thailand require confirmation
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTLKKSLLVLFFLGTISLSLCEQERAADDEDNGEVEEVKRGLFTLIKGAVKMIGKTVAK
EAGKTGLELMACKVTNQC
Length 78
Signal peptide class Class-1
References:
1. for MIC/HC50 T. Chen et al. / Genomics 87 (2006) 638-644. Cloning from tissue surrogates: Antimicrobial peptide (esculentin) cDNAs from the defensive skin secretions of Chinese ranid frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLVLFFLGTISLSLC    
Prepro19 EQERAADDEDNGEVEEVKR   
BioactiveEsculentin-2S37NoGLFTLIKGAVKMIGKTVAKEAGKTGLELMACKVTNQC 1.12.6