Entry | Maximin 9/H3 |
Uniprot code | Q4L0B6 |
Fasta | Q4L0B6 |
Peptide names | Maximin 9 Maximin H3 Maximin 9/H3 |
Suborder | Archeobatrachia |
Family | Bombinatoridae |
Genus | Bombina |
Species | Bombina maxima |
Ecozone | Palearctic, Indomalaya |
Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
Antimicrobial & other activities | antibacterial, antimycoplasma; Maximin H3: antibacterial, antifungal |
Tissue | Skin |
Sequence | MNFKYIVAVSFLIASAYARSVKNDEQSLSQRDVLEEESLREIRGIGRKFLGGVKTTFRCG VKDFASKHLYGKRTAEEHEVMKRLEAIMRDLDSLDHPEEASERETRGFNQDEIANLFTKK EKRILGPVLGLVGNALGGLIKKIG |
Length | 144 |
Signal peptide class | Class-3 |
References: | |
1. for MIC/HC50 | Wen-Hui Lee et al. / FEBS Letters 579 (2005) 4443-4448. Maximin 9, a novel free thiol containing antimicrobial peptide with antimycoplasma activity from frog Bombina maxima; R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 18 | MNFKYIVAVSFLIASAYA | |||||
Prepro | 25 | RSVKNDEQSLSQRDVLEEESLREIR | |||||
Bioactive | Maximin 9 | 27 | Yes | GIGRKFLGGVKTTFRCGVKDFASKHLY | 150 | ||
Prepro | 53 | GKRTAEEHEVMKRLEAIMRDLDSLDHPEEASERETRGFNQDEIANLFTKKEKR | |||||
Bioactive | Maximin H3 | 20 | Yes | ILGPVLGLVGNALGGLIKKI | 10.29 | 5.15 |