Entry | Maximin 4/H3 type 4 |
Uniprot code | Q58T42 |
Fasta | Q58T42 |
Peptide names | Maximin 4/H3 type 4 Maximin 4 Maximin H3 |
Suborder | Archeobatrachia |
Family | Bombinatoridae |
Genus | Bombina |
Species | Bombina maxima |
Ecozone | Palearctic, Indomalaya |
Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
Antimicrobial & other activities | antibacterial, antifungal, anticancer; Maximin H3: antibacterial, antifungal |
Tissue | Skin |
Sequence | MNFKYIIAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGVLLSAGKAALKGL AKVLAEKYANGKRTAEEHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQDEIAKEKRIL GPVLGLVGNALGGLIKKIG |
Length | 139 |
Signal peptide class | Class-3 |
References: | |
1. for MIC/HC50 | R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 18 | MNFKYIIAVSFLIASAYA | |||||
Prepro | 25 | RSVQNDEQSLSQRDVLEEESLREIR | |||||
Bioactive | Maximin 4 | 27 | Yes | GIGGVLLSAGKAALKGLAKVLAEKYAN | 1.03 | 1.03 | |
Prepro | 48 | GKRTAEEHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQDEIAKEKR | |||||
Bioactive | Maximin H3 | 20 | Yes | ILGPVLGLVGNALGGLIKKI | 10.29 | 5.15 |