Maximin 1/H12

Entry Maximin 1/H12
Uniprot code Q58T87
Fasta Q58T87
Peptide names Maximin 1/H12 Maximin 1 Maximin-H12
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal, anticancer
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKILGGVKTALKGA
LKELASTYANGKRTAEEHEVMKRLEVVMRDLDSLDYPEEASERETRDFNQEEIANLYTKK
EKRLLGPVLGLVSNALGGLLKNIG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSEENDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 127YesGIGTKILGGVKTALKGALKELASTYAN 7.297.29
Prepro53 GKRTAEEHEVMKRLEVVMRDLDSLDYPEEASERETRDFNQEEIANLYTKKEKR   
BioactiveMaximin H1220YesLLGPVLGLVSNALGGLLKNI