Entry
Aurein 2.2
Uniprot code
Q5K0E6
Fasta
Q5K0E6
Peptide names
Aurein 2.2
Suborder
Neobatrachia
Family
Hylidae
Genus
Litoria
Species
Litoria aurea
Ecozone
Australasia
Distribution
Eastern New South Wales, south of the Richmond River, Australia; introduced into New Zealand, New Caledonia, and the New Hebrides Island
Antimicrobial & other activities
antibacterial, anticancer, nNOS inhibitor
Tissue
Skin
Sequence
MAFLKKSLFLVLFLGLVSLSICEKEKRQNEEDEDENEAANHEEGSEEKRGLFDIVKKVVG
Length
72
Signal peptide class
Class-1
References:
2. for other activities
M.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
22
MAFLKKSLFLVLFLGLVSLSIC
Prepro 27 EKEKRQNEEDEDENEAANHEEGSEEKR Bioactive Aurein 2.2 16 Yes GLFDIVKKVVGALGSL