| Entry | Kininogen-1a |
| Uniprot code | Q7T3L1 |
| Fasta | Q7T3L1 |
| Peptide names | Maximakinin Kininogen-1a Bradykinin Bombinakinin-GAP |
| Suborder | Archeobatrachia |
| Family | Bombinatoridae |
| Genus | Bombina |
| Species | Bombina maxima |
| Ecozone | Palearctic, Indomalaya |
| Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
| Antimicrobial & other activities | Bombinakinin-GAP: inducing significant decrease in food intake in rats, inhibits the bradykinin-induced in vitro relaxation of rat arterial smooth muscle |
| Tissue | Skin |
| Sequence | MRLWFCLSFFIVLCLEHFTGTLADERNVPESEEKTEQFLRDLPKINRKGPRPPGFSPFRG KFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHS QSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLR DLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPK INRKGPRPPGFSPFRGKFHSQSLRDMYEIKQYKTAHGRPPICAPGEQCPIWVGK |
| Length | 294 |
| Signal peptide class | Class-5 |
| References: | |
| 2. for other activities | R. Lai et al. / Peptides 24 (2003) 199-204. Bombinakinin M gene associated peptide, a novel bioactive peptide from skin secretions of the toad Bombina maxima; L. Wang et al. / Peptides 31 (2010) 979-982. Peptide DV-28 amide: An inhibitor of bradykinin-induced arterial smooth muscle relaxation encoded by Bombina orientalis skin kininogen-2 |
| Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
| Signal | 23 | MRLWFCLSFFIVLCLEHFTGTLA | |||||
| Prepro | 17 | DERNVPESEEKTEQFLR | |||||
| Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
| Bioactive | Bradykinin | 16 | No | RPPGFSPFRGKFHSQS | |||
| Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
| Bioactive | Bradykinin | 16 | No | RPPGFSPFRGKFHSQS | |||
| Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
| Bioactive | Bradykinin | 16 | No | RPPGFSPFRGKFHSQS | |||
| Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
| Bioactive | Bradykinin | 18 | No | GPRPPGFSPFRGKFHSQS | |||
| Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
| Bioactive | Bradykinin | 16 | No | RPPGFSPFRGKFHSQS | |||
| Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
| Bioactive | Bradykinin | 16 | No | RPPGFSPFRGKFHSQS | |||
| Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
| Bioactive | Bradykinin | 16 | No | RPPGFSPFRGKFHSQS | |||
| Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
| Bioactive | Bradykinin | 16 | No | RPPGFSPFRGKFHSQS | |||
| Bioactive | Bombinakinin-GAP | 28 | No | DMYEIKQYKTAHGRPPICAPGEQCPIWV |