PBN1

Entry PBN1
Uniprot code Q800R3
Fasta Q800R3
Peptide names PBN1 Phylloseptin-B1 DRP-PBN1
Suborder Neobatrachia
Family Hylidae
Genus Phyllomedusa
Species Phyllomedusa bicolor
Ecozone Neotropic
Distribution Amazon Basin in Brazil, Colombia, Bolivia, and Peru; the Guianan region of Venezuela and the Guianas. Possibly to be found in eastern Ecuador
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MAFLKKSLFLVLFLGLVSLSICEEEKRETEEKEYDQGEDDKSEEKRFLSLIPHIVSGVAA
LAKHLG
Length 66
Signal peptide class Class-1
References:
1. for MIC/HC50 D. Vanhoye et al. / Biochemistry 43 (2004) 8391-8409. Membrane Association, Electrostatic Sequestration, and Cytotoxicity of Gly-Leu-Rich Peptide Orthologs with Differing Functions


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MAFLKKSLFLVLFLGLVSLSIC    
Prepro24 EEEKRETEEKEYDQGEDDKSEEKR   
BioactivePBN120YesFLSLIPHIVSGVAALAKHLG  12.5