Caerin 1.13

Entry Caerin 1.13
Uniprot code Q800R7
Fasta Q800R7
Peptide names Caerin 1.13
Suborder Neobatrachia
Family Hylidae
Genus Litoria
Species Litoria caerulea
Ecozone Australasia
Distribution Northern and eastern Australia (except for the Victoria and Tasmania); islands in the Torres Straits; New Guinea (northern lowlands, southern lowlands, and Vogelkop Peninsula); introduced into New Zealand
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MASLKKSLFLVLFLGFVSVSICEEEKRQEDEDENEEEGENQEEGSEEKRGLLSVLGSLKL
IVPHVVPLIAEHLG
Length 74
Signal peptide class Class-1
References:
2. for other activities D. Vanhoye et a. / European Journal of Biochemistry 270 (2003) 2068-2081. Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MASLKKSLFLVLFLGFVSVSIC    
Prepro27 EEEKRQEDEDENEEEGENQEEGSEEKR   
BioactiveCaerin 1.1324YesGLLSVLGSLKLIVPHVVPLIAEHL