Entry | Kininogen-1c |
Uniprot code | Q90W88 |
Fasta | Q90W88 |
Peptide names | Maximakinin Kininogen-1c Bradykinin |
Suborder | Archeobatrachia |
Family | Bombinatoridae |
Genus | Bombina |
Species | Bombina maxima |
Ecozone | Palearctic, Indomalaya |
Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
Antimicrobial & other activities | contraction of small intestine smooth muscle cells, relaxation of arterial smooth muscle cells |
Tissue | Skin |
Sequence | MRLWFCLSLFIVLCLEHFPGTLADERNVPESEEKTEQFLRDLPKINRKGPRPPGFSPFRG KFHSQTLRDLPKINRKGPRPPGFSPFRGKFHSQTLRDLPKINRKGPRPPGFSPFRGKFHS QSLRDLPKINRKGPRPPGFSPFRGKFHSQSHV |
Length | 152 |
Signal peptide class | Class-5 |
References: | |
2. for other activities | T. Chen et al. / Peptides 23 (2002) 1547-1555. Bradykinins and their precursor cDNAs from the skin of the fire-bellied toad (Bombina orientalis) |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 23 | MRLWFCLSLFIVLCLEHFPGTLA | |||||
Prepro | 17 | DERNVPESEEKTEQFLR | |||||
Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
Bioactive | Bradykinin | 9 | No | RPPGFSPFR | |||
Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
Bioactive | Bradykinin | 9 | No | RPPGFSPFR | |||
Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
Bioactive | Bradykinin | 9 | No | RPPGFSPFR | |||
Bioactive | Maximakinin | 19 | No | DLPKINRKGPRPPGFSPFR | |||
Bioactive | Bradykinin | 9 | No | RPPGFSPFR |